Département de chimie

Groupe de recherche
Contacts & Liens
  1. M. Zhang, N. Levaray, J. Richard-Daniel, K.C. Waldron, X.X. Zhu*, “Cholic acid dimers as invertible amphiphilic pockets: synthesis, molecular modeling, and inclusion studies”, Canadian Journal of Chemistry, 95(7), 2017, 792-798 (DOI: 10.1139/cjc-2016-0621).
  2. M. Zhang, C. Fives, K.C. Waldron, and X.X. Zhu*, “Self-Assembly of a Bile Acid Dimer in Aqueous Solutions: From Nanofibers to Nematic Hydrogels” Langmuir, 33(4), 2017, 1084–1089. (DOI: 10.1021/acs.langmuir.6b04033).
  3. G. Ghafourifar and K.C. Waldron*, “Fluorescence microscopy imaging of an immobilized enzyme microreactor to investigate glutaraldehyde-mediated crosslinking of chymotrypsin”, Analytical Letters, 49(4), 2016, 589-600. (DOI: 10.1080/00032719.2015.1075128).
  4. M. Zhang, S. Strandman, K.C. Waldron, X.X. Zhu*, “Supramolecular hydrogelation with bile acid derivatives: Structures, properties and applications (Review)”, Journal of Materials Chemistry B, 4, 2016, 7506 – 7520. (DOI: 10.1039/C6TB02270G).
  5. M. Zhang, K.C. Waldron, X.X. Zhu*, “Formation of Molecular Hydrogels from a Bile Acid Derivative and Selected Carboxylic Acids”, RSC Advances, 6, 2016, 35436-35440. (DOI: 10.1039/c6ra04536g).
  6. G. Ghafourifar and K.C. Waldron*, “Capillary Electrophoretic Peptide Mapping to Probe the Immobilization/Digestion Conditions of Glutaraldehyde-crosslinked Chymotrypsin”, Current Analytical Chemistry, 12(1), 2016, 65-73. (DOI: 10.2174/1573411011666150716163727).
  7. P. Lebel, K.C. Waldron and A. Furtos*, “Rapid determination of 24 synthetic and natural cannabinoids for LC-MS/MS screening in natural products and drug inspection applications”, Current Trends in Mass Spectrometry - Supplement to LCGC North America, v.13(1), March 02, 2015, 8-14. Invited submission. (http://www.chromatographyonline.com/special-issues-03-02-2015).
  8. P. Lebel, J. Gagnon, A. Furtos, K.C. Waldron*, “A rapid, quantitative liquid chromatography-mass spectrometry screening method for 71 active and 11 natural erectile dysfunction ingredients present in potentially adulterated or counterfeit products”, Journal of Chromatography A, 1343, 2014, 143-151. (DOI: 10.1016/j.chroma.2014.03.078).
  9. G. Ghafourifar, A. Fleitz and K.C. Waldron*, “Development of glutaraldehyde-crosslinked chymotrypsin and an in situ immobilized enzyme microreactor with peptide mapping by capillary electrophoresis”, Electrophoresis, 34(12), 2013, 1804-1811 (DOI: 10.1002/elps.201200663).
  10. M-C. Tang, A. Nisole, J. Pelletier, C. Dupont and K.C. Waldron*, “Chemical Profiling of the Deacetylase Activity of Acetyl Xylan Esterase A (AxeA) Variants on Chitooligosaccharides using Hydrophilic Interaction Chromatography–Mass Spectrometry”, Journal of Biotechnology, 155, 2011, 257-265.  (DOI: 10.1016/j.jbiotec.2011.06.041).
  11. N. Kaur, J-L. Cabral, A. Morin and K.C. Waldron*, "Headspace Stir Bar Sorptive Extraction–GC/MS Characterization of the Diluted Vapor Phase of Cigarette Smoke Delivered to an In Vitro Cell Exposure Chamber", J. Chromatography A, 1218, 2011, 324-333. (DOI: 10.1016/j.chroma.2010.11.035).
  12. N. Kaur, M. Lacasse, J-P. Roy, J-L. Cabral, J. Adamson, G. Errington, K.C. Waldron, M. Gaça and A. Morin*, "Evaluation of Precision and Accuracy of the Borgwaldt RM20S® Smoking Machine Designed for In Vitro Exposure", Inhalation Toxicology, 22(14), 2010, 1174-1183. (DOI: 10.3109/08958378.2010.533840).
  13. C. Dartiguenave, H. Hamad and K.C. Waldron*, “Immobilization of Trypsin onto 1,4 Diisothiocyanatobenzene-Activated Porous Glass for Microreactor–Based Peptide Mapping by Capillary Electrophoresis: Effect of Calcium Ions on the Immobilization Procedure”, Analytica Chimica Acta, 663(2), 2010, 198-205. (DOI: 10.1016/j.aca.2010.01.042)
  14. G. Roman-Gusetu, K.C. Waldron* and D. Rochefort, “Development of an enzymatic microreactor based on microencapsulated laccase with off-line capillary electrophoresis for measurement of oxidation reactions”, Journal of Chromatography A, 1216, 2009, 8270-8276. (DOI: 10.1016/j.chroma.2009.08.069).
  15. N. Kaur, M. Lacasse, A. Fürtös, K.C. Waldron* and A. Morin*, “Sequential fractionation with concurrent chemical and toxicological characterization of the combustion products of chlorogenic acid”, Journal of Chromatography A, 1216, 2009, 4703-4712. (DOI: 10.1016/j.chroma.2009.04.007).
  16. I. Migneault, C. Dartiguenave, J. Vinh, M.J. Bertrand and K.C. Waldron*, “Two Glutaraldehyde-Immobilized Trypsin Preparations for Peptide Mapping by Capillary Zone Electrophoresis, Liquid Chromatography and Mass Spectrometry”, Journal of Liquid Chromatography and Related Techniques, 31, 2008, 789-806. (DOI: 10.1080/10826070801890413).
  17. M. Elsabahy, M. Zhang, S-M. Gan, K.C. Waldron and J-C. Leroux*, “Synthesis and Enzymatic Stability of PEGylated Oligonucleotide Duplexes and their Self-assemblies with Polyamidoamine Dendrimers”, Soft Matter, 4, 2008, 294-302. (DOI: 10.1039/b714221h).
  18. M. Schirm, I. Schoenhofen, S.M. Logan, K.C. Waldron and P. Thibault*, “Identification of Unusual Bacterial Glycosylation by Tandem Mass Spectrometry Analyses of Intact Proteins" Analytical Chemistry, 77(23), 2005, 7774-7782. (DOI: 10.1021/ac051316y).
  19. M-E. Beaudoin, J. Gauthier, I. Boucher and K.C. Waldron* “Capillary Electrophoresis Separation of a mixture of Chitin and Chitosan Oligosaccharides Derivatized using a Modified Fluorophore Conjugation Procedure” Journal of Separation Science, 12, 2005, 1390-1398. (DOI 10.1002/jssc.200500022).
  20. M. Walles, Y. Gu, C. Dartiguenave , F. M. Musteata, K. Waldron, D. Lubda, J. Pawliszyn*, “Approaches for Coupling Solid-Phase Microexraction to Nanospray”, Journal of Chromatography A, 1067(1-2), 2005, 197-205.  (DOI : 10.1016/j.chroma.2004.11.047).
  21. I. Migneault, C. Dartiguenave, M.J. Bertrand and K.C. Waldron*, “Glutaraldehyde: Behavior in Aqueous Solution, Reaction with Proteins, and Application to Enzyme Crosslinking (Review Article)”, BioTechniques, 37(5), 2004, 790-796, 798-802. (http://www.biotechniques.com/multimedia/archive/00037/BTN_A_04375RV01_O_37190a.pdf).
  22. I. Migneault, C. Dartiguenave, J. Vinh, M.J. Bertrand and K.C. Waldron*, “Comparison of two glutaraldehyde immobilization techniques for solid-phase tryptic peptide mapping of human hemoglobin by capillary zone electrophoresis and mass spectrometry”, Electrophoresis, 25, 2004, 1367-1378.  (DOI: 10.1002/elps.200305861).
  23. M. Aouffen, J. Paquin, A. Fürtös, K.C. Waldron and M-A. Mateescu, “Oxidative Aggregation of Ceruloplasmin Induced by Hydrogen Peroxide is Prevented by Pyruvate” Free Radical Research, 38(1), 2004, 19-26.
  24. C. Hémond, A. Fürtös-Matei and K.C. Waldron*, “A Comparison between Electrokinetic Capillary Chromatography and Absorption Spectroscopy for the Analysis of Peptide-Micelle Association by Weak Hydrophobic Interactions”, Electrophoresis, 24(5), 2003, 816-823.
  25. I. Migneault, C. Dartiguenave, H. Hamad, K.C. Waldron*, M.J. Bertrand and J. Vinh, “Comparison of Trypsin Immobilization Techniques With and Without a Solid Support for Peptide Mapping”, ASMS-2003 (Proceedings of the 51st Annual Conference on Mass Spectrometry and Allied Topics, Montréal, Canada, June 8-12, 2003).
  26. J-L. Cabral, K.C. Waldron* and F. Monette, “Analysis of Total Phosphorous in Wastewater by Microwave Digestion-Capillary Electrophoresis with Indirect UV Detection”, in “EnviroAnalysis 2002 (Proceedings of the 4th Biennial International Conference on Monitoring and Measurement of the Environment, Toronto, Canada, May 27-30, 2002)”, Clement, R. and Burk, B. (Eds.), pp. 473-478.
  27. A. Fürtös-Matei, S.A. St-Pierre and K.C. Waldron*, “Capillary Electrophoresis Separation of Endogenous N-truncated Neuropeptide Y Fragments”, International Journal of Biochromatography 6(3), 2001, 219-230.
  28. É. Bonneil and K.C. Waldron*, “On-line System for Peptide Mapping by Capillary Electrophoresis at Submicromolar Concentrations”, Talanta 53(3), 2000, 687-699.
  29. A. Fürtös-Matei , R. Day, S.A. St-Pierre, L.G. St-Pierre and K.C. Waldron*, “Micellar Electrokinetic Chromatography Separations of Dynorphin Peptide Analogs” Electrophoresis, 21(4), 2000, 715-723.
  30. É. Bonneil, M. Mercier and K.C. Waldron*, “Reproducibility of a Solid-Phase Trypsin Microreactor for Peptide Mapping by Capillary Electrophoresis” Analytica Chimica Acta, 404, 2000, 29-45.
  31. J. Luo, R. Hausler and K.C. Waldron*, “Determination of trace aluminum in water and wastewater by capillary electrophoresis”, in EnviroAnalysis 2000 (Proceedings of the 3rd Biennial International Conference on Monitoring and Measurement of the Environment, Ottawa, Canada, May 8 - 11, 2000), Clement, R. and Burk, B. (Eds.), pp. 101-106.
  32. É. Bonneil* and K.C. Waldron*, “On-line Solid-phase Preconcentration for Sensitivity Enhancement in Capillary Electrophoresis [Review]”, Journal of Capillary Electrophoresis 6(3/4), 1999, 61-73.
  33. É. Bonneil and K.C. Waldron*, “Characterization of a Solid-phase Extraction Device for Discontinuous On-line Preconcentration in Capillary Electrophoresis-based Peptide Mapping” Journal of Chromatography B, 736, 1999, 273-287.
  34. J. Li and K.C. Waldron*, “Estimation of the pH-Independent Binding Constants of Alanylphenylalanine and Leucylphenylalanine with -Cyclodextrin in the Presence of Urea”. Electrophoresis, 20, 1999, 171-179.
  35. J. Li and K.C. Waldron*, “Effect of Surfactant Concentration on the Determination of trans,trans-Muconic Acid in Urine by Cationic Micellar Electrokinetic Chromatography with Thermo-Optical Absorbance Detection”. Journal of Liquid Chromatography, 22, 1999, 1919-1933.
  36. D.M. Paquette, R. Sing, P.R. Banks* and K.C. Waldron*, “Capillary Electrophoresis with Laser-Induced Native Fluorescence Detection for Profiling Body Fluids” Journal of Chromatography B., 714, 1998, 47-57.
  37. A. Fürtös-Matei, J. Li and K.C. Waldron*, “Micellar Electrokinetic Chromatographic Study of the Interaction Between Enkephalin Peptide Analogs and Charged Micelles”, Journal of Chromatography B., 695, 1997, 39-47.
  38. K.C. Waldron* and J. Li, “Investigation of a Pulsed-Laser Thermo-optical Absorbance Detector for the Determination of Food Preservatives Separated by Capillary Electrophoresis”, Journal of Chromatography B., 683, 1996, 47-54.
  39. K.C. Waldron, X-F. Li, M. Chen, I. Ireland, D. Lewis, M. Carpenter and N.J. Dovichi*, “Miniaturized Protein Microsequencer with PTH Amino Acid Identification by Capillary Electrophoresis I. Argon Pressurized Delivery System for Adsorptive and Covalent Sequencing”, Talanta, 44, 1997, 383-399.
  40. X.F. Li, H. Ren, M. Qi, D.F. Lewis, I.D. Ireland, K.C. Waldron et N.J. Dovichi*, “Protein Sequencing Using Microreactors and Capillary Electrophoresis with Thermo-optical Absorbance Detection”, in Techniques in Protein Chemistry VIII (Proceedings of the Tenth Symposium of the Protein Society), D.R. Marshak (Ed.), Academic Press, San Diego, 1997, pp. 3-14.
  41. X-F. Li, K.C. Waldron, J. Black, D. Lewis, I. Ireland and N.J. Dovichi*, “Miniaturized Protein Microsequencer with PTH Amino Acid Identification by Capillary Electrophoresis II. Syringe-pump Based System for Covalent Sequencing”, Talanta, 44, 1997, 401-411.
  42. K.C. Waldron, M. Carpenter, I. Ireland, D. Lewis, X.F. Li et N.J. Dovichi*, “High Sensitivity Analysis of PTH Amino Acids”, in Methods in Protein Structure Analysis (Proceedings of the Tenth International Conference on Methods in Protein Structure Analysis), M.Z. Atassi et E. Appella, (Eds.), Plenum Press, New York, 1995, pp 49-55.
  43. M. Chen, K.C. Waldron, Y. Zhao and N.J. Dovichi*, “Micellar Capillary Electrophoresis Separation and Thermo-optical Absorbance Detection of Products from Manual Peptide Sequencing”, Electrophoresis, 15, 1994, 1290-1294.
  44. N.J. Dovichi*, K.C. Waldron, M. Chen and I. Ireland, “High Sensitivity Analysis of PTH Amino Acids”, Journal of Protein Chemistry, MPSA Short Communications, 13, 1994, 470-471.
  45. K.C. Waldron, M. Chen, Y. Zhao et N.J. Dovichi*, “Development of a Highly Miniaturized Peptide Sequencer” in Peptides: Chemistry, Structure and Biology (Proceedings of the Thirteenth American Peptide Symposium, Edmonton, 20-25 June 1993), Hodges, R.S. et Smith, J.A. (Eds.), Escom, Leiden, The Netherlands, 1994, pp 224-227.
  46. K.C. Waldron and N.J. Dovichi*, "Sub-Femtomole Determination of PTH-Amino Acids: Capillary Electrophoresis and Thermo-optical Detection”, Analytical Chemistry, 64, 1992, 1396-1399.
  47. J.Y. Zhao, K.C. Waldron, J. Miller, J.Z. Zhang, H. Harke and N.J. Dovichi*, "Attachment of a Single Fluorescent Label to Peptides for Determination by Capillary Zone Electrophoresis", Journal of Chromatography, 608, 1992, 239-242.
  48. J.Y. Zhao, K.C. Waldron, D.Y. Chen et N.J. Dovichi*, “Attomole and Sub-Attomole Determination of Thiohydantoin Derivatives of Amino Acids by Capillary Zone Electrophoresis Separation and Laser-Based Detection”, in Frontiers and New Horizons in Amino Acid Research (Proceedings of the First Biennial International Conference on Amino Acid Research, Kyoto, 13-19 August 1991), Katsuji Takai (Ed.), Elsevier, Amsterdam, 1992, pp 239-248.
  49. K.C. Waldron, J. Miller and N.J. Dovichi*, “Attomole Determination Of Phenylthiohydantoin Derivatives of Amino Acids by Capillary Zone Electrophoresis Separation and Ultraviolet-Laser Excited Thermo-Optical Absorbance Detection”, Analytical Sciences, 7 (Supplement), 1991, 959-961.
  50. K.C. Waldron, S. Wu, C.W. Earle, H.R. Harke and N.J. Dovichi*, "Capillary Zone Electrophoresis Separation and Laser-Based Detection of both Fluorescein Thiohydantoin and Dimethylaminoazobenzene Thiohydantion Derivatives of Amino Acids", Electrophoresis, 11, 1991, 777-780.
  51. K. Cameron [Waldron], M.C. Depew and J.K.S. Wan*, “Pulsed Microwave Catalytic Decomposition of Olefins”, Research on Chemical Intermediates, 16, 1991, 57-70.


Articles Soumis



Articles En Préparation

G. Ghafourifar, B. Fleury, K.C. Waldron, “A study of the chymotrypsin-IMER digestion efficiency as a function of substrate size”.



“Continuous Biochemical Reactor for Analysis of Sub-Picomole Quantities of Complex Organic Molecules and Method of Operation Thereof”, describing the design, construction and operation of a miniaturized polypeptide microsequencer. US Patent 5,415,841 issued May 16, 1995 and US Patent 5,565,171 issued October 15, 1996, USA. Inventeurs: N.J. Dovichi et K.C. Waldron.



“PepCE”, un logiciel (Visual Basic) permettant la simulation des séparations de peptides par électrophorèse capillaire (CE) basée sur les séquences primaires; simulation des cartes peptidiques par CE provenant des protéines connues pour une gamme d’enzymes protéolytiques. Inventeurs: J. Li et K.C. Waldron, PepCE v. 1, 1995.

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